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產(chǎn)品規(guī)格
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BN40316R-100ul
100ul
￥2360.00
交叉反應(yīng)：Mouse(predicted:Human,Rat,Cow,Horse) 推薦應(yīng)用：WB,IHC-P,IHC-F,ICC,IF,ELISA
BN40316R-200ul
200ul
￥3490.00
交叉反應(yīng)：Mouse(predicted:Human,Rat,Cow,Horse) 推薦應(yīng)用：WB,IHC-P,IHC-F,ICC,IF,ELISA
產(chǎn)品描述
| 英文名稱 | SOX8 |
| 中文名稱 | 核轉(zhuǎn)錄因子SOX8抗體 |
| 別 名 | SOX 8; Sox8; SOX8_HUMAN; SRY (sex determining region Y) box 8; SRY box 8; SRY box containing gene 8; Transcription factor SOX 8; Transcription factor SOX-8; Transcription factor SOX8. |
| 研究領(lǐng)域 | 神經(jīng)生物學 轉(zhuǎn)錄調(diào)節(jié)因子 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse, (predicted: Human, Rat, Cow, Horse, ) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 47kDa |
| 細胞定位 | 細胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SOX8:101-200/446 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 產(chǎn)品介紹 | Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal. Function: May play a role in central nervous system, limb and facial development. May be involved in male sex determination. Binds the consensus motif 5'-[AT][AT]CAA[AT]G-3'. Subcellular Location: Nucleus. Tissue Specificity: Contains 1 HMG box DNA-binding domain. Similarity: Contains 1 HMG box DNA-binding domain. SWISS: P57073 Gene ID: 30812 Database links: Entrez Gene: 30812 Human Entrez Gene: 20681 Mouse Omim: 605923 Human SwissProt: P57073 Human SwissProt: Q04886 Mouse Unigene: 243678 Human Unigene: 258220 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
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